These measures are not interchangeable.
OSDI and SEEQ are patient-reported symptom scores; tear-breakup time measures tear-film stability; Schirmer testing measures tear production. A lower symptom score is generally better, while longer breakup time and greater Schirmer wetting are generally better. Study methods and thresholds still matter.
4source studies
8procedure arms
45verified observations
3procedures represented

Reported measurements

Each number links to its publication and retains the source table or abstract location.

MODERATE evidencePROSPECTIVE COHORTVerified evidence

Dry Eye Disease following Refractive Surgery: A 12-Month Follow-Up of SMILE versus FS-LASIK in High Myopia (2015)

SMILE47 enrolled patients47 enrolled eyes
1 month47 observed patients
6.28 s
47 patients
Source · Table 3
Tear breakup time
0.77
47 patients
Source · Table 4
Salisbury Eye Evaluation Questionnaire dry-eye score
3 months47 observed patients
8.21 s
47 patients
Source · Table 3
Tear breakup time
0.34
47 patients
Source · Table 4
Salisbury Eye Evaluation Questionnaire dry-eye score
6 months47 observed patients
9.57 s
47 patients
Source · Table 3
Tear breakup time
0.13
47 patients
Source · Table 4
Salisbury Eye Evaluation Questionnaire dry-eye score
12 months47 observed patients
9.83 s
47 patients
Source · Table 3
Tear breakup time
0.04
47 patients
Source · Table 4
Salisbury Eye Evaluation Questionnaire dry-eye score
MODERATE evidencePROSPECTIVE COHORTVerified evidence

Dry Eye Disease following Refractive Surgery: A 12-Month Follow-Up of SMILE versus FS-LASIK in High Myopia (2015)

LASIK43 enrolled patients43 enrolled eyes
1 month43 observed patients
6.53 s
43 patients
Source · Table 3
Tear breakup time
1.56
43 patients
Source · Table 4
Salisbury Eye Evaluation Questionnaire dry-eye score
3 months43 observed patients
7.42 s
43 patients
Source · Table 3
Tear breakup time
1.21
43 patients
Source · Table 4
Salisbury Eye Evaluation Questionnaire dry-eye score
6 months43 observed patients
8.19 s
43 patients
Source · Table 3
Tear breakup time
0.49
43 patients
Source · Table 4
Salisbury Eye Evaluation Questionnaire dry-eye score
12 months43 observed patients
9.30 s
43 patients
Source · Table 3
Tear breakup time
0.14
43 patients
Source · Table 4
Salisbury Eye Evaluation Questionnaire dry-eye score
MODERATE evidencePROSPECTIVE COHORTVerified evidence

Comparison of dry eye and corneal sensitivity between small incision lenticule extraction and femtosecond LASIK for myopia (2013)

SMILE38 enrolled patients38 enrolled eyes
1 week37 observed patients
23.95
37 patients
Source · Table 3
Ocular Surface Disease Index
4.32 s
37 patients
Source · Table 3
Tear breakup time
13.51 mm
37 patients
Source · Table 3
Schirmer I test without anesthesia
1 month37 observed patients
16.72
37 patients
Source · Table 3
Ocular Surface Disease Index
5.68 s
37 patients
Source · Table 3
Tear breakup time
12.11 mm
37 patients
Source · Table 3
Schirmer I test without anesthesia
3 months36 observed patients
12.05
36 patients
Source · Table 3
Ocular Surface Disease Index
5.03 s
36 patients
Source · Table 3
Tear breakup time
14.14 mm
36 patients
Source · Table 3
Schirmer I test without anesthesia
6 months36 observed patients
8.47
36 patients
Source · Table 3
Ocular Surface Disease Index
7.06 s
36 patients
Source · Table 3
Tear breakup time
13.28 mm
36 patients
Source · Table 3
Schirmer I test without anesthesia
MODERATE evidencePROSPECTIVE COHORTVerified evidence

Comparison of dry eye and corneal sensitivity between small incision lenticule extraction and femtosecond LASIK for myopia (2013)

LASIK33 enrolled patients33 enrolled eyes
1 week32 observed patients
18.78
32 patients
Source · Table 3
Ocular Surface Disease Index
4.70 s
32 patients
Source · Table 3
Tear breakup time
10.00 mm
32 patients
Source · Table 3
Schirmer I test without anesthesia
1 month31 observed patients
17.77
31 patients
Source · Table 3
Ocular Surface Disease Index
3.77 s
31 patients
Source · Table 3
Tear breakup time
10.90 mm
31 patients
Source · Table 3
Schirmer I test without anesthesia
3 months30 observed patients
16.22
30 patients
Source · Table 3
Ocular Surface Disease Index
4.43 s
30 patients
Source · Table 3
Tear breakup time
13.73 mm
30 patients
Source · Table 3
Schirmer I test without anesthesia
6 months30 observed patients
15.50
30 patients
Source · Table 3
Ocular Surface Disease Index
4.97 s
30 patients
Source · Table 3
Tear breakup time
13.17 mm
30 patients
Source · Table 3
Schirmer I test without anesthesia