Ocular Evidence
Evidence database / Studies / palmer-2025-klex-577-eyes
MODERATE evidenceRETROSPECTIVEVerified evidence

Visual outcomes for the initial 500 eyes treated with keratorefractive lenticule extraction for myopia and myopic astigmatism at a single site

Palmer BL, Sitto MM, Davis JC, Hoopes PC, Moshirfar M · Medical Hypothesis, Discovery & Innovation Ophthalmology Journal · 2025

Source
314enrolled patients*
577enrolled eyes*
1structured arms
365maximum standardized days follow-up

* Descriptive sum of reported arm counts. “≥” indicates that one or more arm counts were not reported; missing values are not treated as zero.

Study arm

KLEx

SMILE

Population

Patients
314
Eyes
577
Bilateral treatment
Not reported
Age range
Not reported
Sphere range
Not reported
Cylinder range
Not reported
Spherical equivalent
Not reported
Corneal thickness
Not reported

Eligibility definition

Inclusion
Myopia from -1.00 to -9.25 D, cylinder up to 3.00 D, and preoperative CDVA 20/20 or better.

Exclusion
Not structured

Reported outcomes by follow-up

OutcomeFollow-upFollow-up sampleResultReported fractionProvenance
UDVA 20/20 or better
efficacy
12 months440 eyes81.0%denominator: 440 eyes
VERIFIED
MRSE within ±0.50 D
predictability
12 months440 eyes85.0%denominator: 440 eyes
VERIFIED
Refraction within ±1.00 D
efficacy
12 months440 eyes97.0%denominator: 440 eyes
VERIFIED
Mean postoperative spherical equivalent
refractive
12 months440 eyes0.04 DNot reported
VERIFIED
Lost at least 2 lines of CDVA
safety
12 months440 eyes0%0 / 440 eyes
VERIFIED

Complications

No structured complication observations are available for this arm. This means “not reported in this dataset,” not zero complications.