Single-Step Transepithelial PRK vs Alcohol-Assisted PRK in Myopia and Compound Myopic Astigmatism Correction

Evidence database / Studies / kaluzny-2016-transprk-alcohol-prk

148enrolled patients*

276enrolled eyes*

2structured arms

90maximum standardized days follow-up

* Descriptive sum of reported arm counts. “≥” indicates that one or more arm counts were not reported; missing values are not treated as zero.

Study arm

Single-step transepithelial PRK

TransPRK

Population

Patients: 93
Eyes: 173
Bilateral treatment: Not reported
Age range: Not reported
Sphere range: Not reported
Cylinder range: Not reported
Spherical equivalent: Not reported
Corneal thickness: Not reported

Eligibility definition

Inclusion
Myopia or compound myopic astigmatism.

Exclusion
Not structured

Reported outcomes by follow-up

Outcome	Follow-up	Follow-up sample	Result	Reported fraction	Provenance
UDVA 20/20 or better efficacy	3 months	145 eyes	97.0%	denominator: 145 eyes	VERIFIED Source
Loss of 1 line of corrected visual acuity safety	3 months	145 eyes	13.0%	denominator: 145 eyes	VERIFIED Source
Mean postoperative spherical equivalent refractive	3 months	145 eyes	-0.14 D	Not reported	VERIFIED Source

Complications

No structured complication observations are available for this arm. This means “not reported in this dataset,” not zero complications.

Study arm

Alcohol-assisted PRK

PRK

Population

Patients: 55
Eyes: 103
Bilateral treatment: Not reported
Age range: Not reported
Sphere range: Not reported
Cylinder range: Not reported
Spherical equivalent: Not reported
Corneal thickness: Not reported

Eligibility definition

Inclusion
Myopia or compound myopic astigmatism.

Exclusion
Not structured

Reported outcomes by follow-up

Outcome	Follow-up	Follow-up sample	Result	Reported fraction	Provenance
UDVA 20/20 or better efficacy	3 months	90 eyes	94.0%	denominator: 90 eyes	VERIFIED Source
Loss of 1 line of corrected visual acuity safety	3 months	90 eyes	21.0%	denominator: 90 eyes	VERIFIED Source
Mean postoperative spherical equivalent refractive	3 months	90 eyes	-0.12 D	Not reported	VERIFIED Source

Complications

No structured complication observations are available for this arm. This means “not reported in this dataset,” not zero complications.

Study design

Prospective, nonrandomized, consecutive case-control study with 3-month follow-up.

Country: Not reported
Publication-reported places: Not reported
Multicenter: Not reported
Prospective: Yes
Randomized: No
Source type: PROSPECTIVE COHORT
Regulator: Not reported

Place metadata may refer to a treatment site, institution or author affiliation. Confirm its role in the linked publication.

Limitations and notes

The abstract reports arm-specific follow-up denominators; no missing-eye outcomes were imputed.

Missing fields are not interpreted as negative findings. Arm counts may not be additive in all study designs.

Study evidence level
A simple, non-GRADE hierarchy based on design: randomized and large regulatory trials are high; prospective cohorts moderate; retrospective observational studies low. Manual review can override this label.