Ocular Evidence
Study-specific comparison

Compare reviewed observations side by side

Each result remains attached to its own study, device, denominator, follow-up, and publication. No averages or head-to-head claims are created.

Corneal laser

LASIK

29 matching study follow-ups

Incidence, severity, and predictors of early postoperative dry eye disease following femtosecond laser-assisted in situ keratomileusis (FS-LASIK): a short-term, single-center retrospective analysis (2026)

1 weekDevice not reportedUnknown eyes
Dry eye symptoms (OSDI ≥13)
25% denominator: 3000 patients
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Incidence, severity, and predictors of early postoperative dry eye disease following femtosecond laser-assisted in situ keratomileusis (FS-LASIK): a short-term, single-center retrospective analysis (2026)

1 monthDevice not reportedUnknown eyes
Dry eye symptoms (OSDI ≥13)
38% denominator: 3000 patients
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Incidence, severity, and predictors of early postoperative dry eye disease following femtosecond laser-assisted in situ keratomileusis (FS-LASIK): a short-term, single-center retrospective analysis (2026)

3 monthsDevice not reportedUnknown eyes
Dry eye symptoms (OSDI ≥13)
15% denominator: 3000 patients
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FDA pivotal clinical study of INNOVEYES LASIK with WaveLight EX500 (2025)

3 monthsAlcon Laboratories, Inc. · WaveLight EX500 with INNOVEYES Sightmap326 eyes
UDVA 20/20 or better
92.3% denominator: 326 eyes
MRSE within ±0.50 D
92% denominator: 326 eyes
Refraction within ±1.00 D
98.5% denominator: 326 eyes
Lost at least 2 lines of CDVA
0% denominator: 330 eyes
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FDA pivotal clinical study of INNOVEYES LASIK with WaveLight EX500 (2025)

6 monthsAlcon Laboratories, Inc. · WaveLight EX500 with INNOVEYES Sightmap330 eyes
UDVA 20/20 or better
91.5% denominator: 330 eyes
MRSE within ±0.50 D
90.9% denominator: 330 eyes
Refraction within ±1.00 D
98.2% denominator: 330 eyes
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FDA pivotal clinical study of INNOVEYES LASIK with WaveLight EX500 (2025)

12 monthsAlcon Laboratories, Inc. · WaveLight EX500 with INNOVEYES Sightmap322 eyes
UDVA 20/20 or better
94.4% denominator: 322 eyes
MRSE within ±0.50 D
94.4% denominator: 322 eyes
Refraction within ±1.00 D
99.7% denominator: 322 eyes
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Myopic Regression After FS-LASIK and SMILE (2024)

3 monthsDevice not reported416 eyes
Spherical-equivalent regression from month 1
-0.17 D denominator: 416 eyes
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Myopic Regression After FS-LASIK and SMILE (2024)

6 monthsDevice not reported416 eyes
Spherical-equivalent regression from month 1
-0.24 D denominator: 416 eyes
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Myopic Regression After FS-LASIK and SMILE (2024)

9 monthsDevice not reported416 eyes
Spherical-equivalent regression from month 1
-0.31 D denominator: 416 eyes
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Myopic Regression After FS-LASIK and SMILE (2024)

12 monthsDevice not reported416 eyes
Spherical-equivalent regression from month 1
-0.32 D denominator: 416 eyes
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Myopic Regression After FS-LASIK and SMILE (2024)

18 monthsDevice not reported416 eyes
Spherical-equivalent regression from month 1
-0.33 D denominator: 416 eyes
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Randomized Clinical Trial Comparing Femtosecond LASIK and Small-Incision Lenticule Extraction (2020)

3 monthsAlcon Laboratories, Inc. · WaveLight EX50070 eyes
UDVA 20/20 or better
87% denominator: 70 eyes
Refraction within ±1.00 D
97% denominator: 70 eyes
Efficacy index
0.99 score
Safety index
1.1 score
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Randomized Clinical Trial Comparing Femtosecond LASIK and Small-Incision Lenticule Extraction (2020)

12 monthsAlcon Laboratories, Inc. · WaveLight EX50070 eyes
UDVA 20/20 or better
83% denominator: 70 eyes
Refraction within ±1.00 D
99% denominator: 70 eyes
Safety index
1.15 score
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Incidence and Clinical Characteristics of Post LASIK Ectasia: A Review of over 30,000 LASIK Cases (2018)

2–8 yearsDevice not reported30167 eyes
Post-LASIK corneal ectasia
0.03% denominator: 30167 eyes
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Symptoms and Satisfaction of Patients in the Patient-Reported Outcomes With Laser In Situ Keratomileusis (PROWL) Studies (2017)

3 monthsDevice not reportedUnknown eyes
Normal OSDI score
66%
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Symptoms and Satisfaction of Patients in the Patient-Reported Outcomes With Laser In Situ Keratomileusis (PROWL) Studies (2017)

6 monthsDevice not reportedUnknown eyes
Normal OSDI score
73%
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Symptoms and Satisfaction of Patients in the Patient-Reported Outcomes With Laser In Situ Keratomileusis (PROWL) Studies (2017)

3 monthsDevice not reportedUnknown eyes
Normal OSDI score
65%
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Chronic dry eye in photorefractive keratectomy and laser in situ keratomileusis: Manifestations, incidence, and predictive factors (2015)

12 monthsDevice not reportedUnknown eyes
Chronic dry-eye incidence
0.8%
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Dry Eye Disease following Refractive Surgery: A 12-Month Follow-Up of SMILE versus FS-LASIK in High Myopia (2015)

1 monthDevice not reported43 eyes
Tear breakup time
6.53 seconds denominator: 43 patients
Salisbury Eye Evaluation Questionnaire dry-eye score
1.56 score denominator: 43 patients
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Dry Eye Disease following Refractive Surgery: A 12-Month Follow-Up of SMILE versus FS-LASIK in High Myopia (2015)

3 monthsDevice not reported43 eyes
Tear breakup time
7.42 seconds denominator: 43 patients
Salisbury Eye Evaluation Questionnaire dry-eye score
1.21 score denominator: 43 patients
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Dry Eye Disease following Refractive Surgery: A 12-Month Follow-Up of SMILE versus FS-LASIK in High Myopia (2015)

6 monthsDevice not reported43 eyes
Tear breakup time
8.19 seconds denominator: 43 patients
Salisbury Eye Evaluation Questionnaire dry-eye score
0.49 score denominator: 43 patients
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Dry Eye Disease following Refractive Surgery: A 12-Month Follow-Up of SMILE versus FS-LASIK in High Myopia (2015)

12 monthsDevice not reported43 eyes
Tear breakup time
9.3 seconds denominator: 43 patients
Salisbury Eye Evaluation Questionnaire dry-eye score
0.14 score denominator: 43 patients
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Single-Step Transepithelial ASLA (SCHWIND) With Mitomycin-C for the Correction of High Myopia: Long-Term Follow-Up (2015)

12 monthsSCHWIND eye-tech-solutions · AMARIS31 eyes
MRSE within ±0.50 D
83.9% denominator: 31 eyes
Mean postoperative spherical equivalent
-0.08 D denominator: 31 eyes
Mean uncorrected distance visual acuity
0.05 logMAR denominator: 31 eyes
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Comparison of visual and refractive outcomes following femtosecond laser-assisted LASIK with SMILE in patients with myopia or myopic astigmatism (2014)

1 dayDevice not reported50 eyes
UDVA 20/20 or better
92% denominator: 50 eyes
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Comparison of visual and refractive outcomes following femtosecond laser-assisted LASIK with SMILE in patients with myopia or myopic astigmatism (2014)

3 monthsDevice not reported50 eyes
UDVA 20/20 or better
84% denominator: 50 eyes
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Comparison of dry eye and corneal sensitivity between small incision lenticule extraction and femtosecond LASIK for myopia (2013)

1 weekDevice not reported32 eyes
Ocular Surface Disease Index
18.78 score denominator: 32 patients
Tear breakup time
4.7 seconds denominator: 32 patients
Schirmer I test without anesthesia
10 mm denominator: 32 patients
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Comparison of dry eye and corneal sensitivity between small incision lenticule extraction and femtosecond LASIK for myopia (2013)

1 monthDevice not reported31 eyes
Ocular Surface Disease Index
17.77 score denominator: 31 patients
Tear breakup time
3.77 seconds denominator: 31 patients
Schirmer I test without anesthesia
10.9 mm denominator: 31 patients
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Comparison of dry eye and corneal sensitivity between small incision lenticule extraction and femtosecond LASIK for myopia (2013)

3 monthsDevice not reported30 eyes
Ocular Surface Disease Index
16.22 score denominator: 30 patients
Tear breakup time
4.43 seconds denominator: 30 patients
Schirmer I test without anesthesia
13.73 mm denominator: 30 patients
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Comparison of dry eye and corneal sensitivity between small incision lenticule extraction and femtosecond LASIK for myopia (2013)

6 monthsDevice not reported30 eyes
Ocular Surface Disease Index
15.5 score denominator: 30 patients
Tear breakup time
4.97 seconds denominator: 30 patients
Schirmer I test without anesthesia
13.17 mm denominator: 30 patients
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Phakic intraocular lens

ICL

10 matching study follow-ups

Comparison of Persistent Postoperative Discomfort 1 Year after Keratorefractive Lenticule Extraction and Implantable Collamer Lens Implantation (2025)

1 yearSTAAR Surgical · EVO Implantable Collamer Lens97 eyes
Postoperative night glare
64.9% denominator: 97 patients
Postoperative halos
63.9% denominator: 97 patients
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Three Year Results from the United States FDA Prospective Multicenter Clinical Study of the EVO/EVO+ Implantable Collamer Lens (2025)

3 yearsSTAAR Surgical · EVO Implantable Collamer Lens629 eyes
MRSE within ±0.50 D
90.7% denominator: 629 eyes
Refraction within ±1.00 D
99% denominator: 629 eyes
Mean postoperative spherical equivalent
-0.12 D
Gained 1 or more lines of corrected visual acuity
48.9% denominator: 629 eyes
Lens exchange rate
0.32% denominator: 629 eyes
Anterior subcapsular cataract rate
0.16% denominator: 629 eyes
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One-Stage Versus Two-Stage Bilateral Implantable Collamer Lens Implantation: A Comparison of Efficacy and Safety (2024)

Mean 1.1 yearsDevice not reported100 eyes
Post-ICL endophthalmitis
0% denominator: 100 eyes
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One-Stage Versus Two-Stage Bilateral Implantable Collamer Lens Implantation: A Comparison of Efficacy and Safety (2024)

Mean 1.3 yearsDevice not reported78 eyes
Post-ICL endophthalmitis
0% denominator: 78 eyes
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A Nationwide Multicenter Study on 1-Year Outcomes of Posterior Chamber Phakic Intraocular Lens Implantation for Low Myopia (2022)

1 yearSTAAR Surgical · EVO Implantable Collamer Lens172 eyes
MRSE within ±0.50 D
91% denominator: 172 eyes
Refraction within ±1.00 D
100% denominator: 172 eyes
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Two-Year Visual Outcomes of Evolution Implantable Collamer Lens and Small Incision Lenticule Extraction for the Correction of Low Myopia (2022)

2 yearsSTAAR Surgical · EVO Implantable Collamer Lens25 eyes
Uncorrected acuity at least as good as preoperative corrected acuity
80% denominator: 25 eyes
MRSE within ±0.50 D
96% denominator: 25 eyes
Lost at least 2 lines of CDVA
0% denominator: 25 eyes
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Eight-Year Outcomes of Implantation of Posterior Chamber Phakic Intraocular Lens With a Central Port for Moderate to High Ametropia (2021)

8 yearsSTAAR Surgical · EVO Implantable Collamer Lens177 eyes
MRSE within ±0.50 D
83% denominator: 177 eyes
Refraction within ±1.00 D
93% denominator: 177 eyes
Cataract requiring lens extraction or exchange
1.7% denominator: 177 eyes
Efficacy index
0.89 score
Safety index
1.18 score
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Five-year outcomes of EVO implantable collamer lens implantation for the correction of high myopia and super high myopia (2021)

5 yearsSTAAR Surgical · EVO Implantable Collamer LensUnknown eyes
MRSE within ±0.50 D
60.47%
Refraction within ±1.00 D
79.07%
Mean postoperative spherical equivalent
-0.67 D
Efficacy index
0.83 score
Safety index
1.03 score
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Five-year outcomes of EVO implantable collamer lens implantation for the correction of high myopia and super high myopia (2021)

5 yearsSTAAR Surgical · EVO Implantable Collamer LensUnknown eyes
MRSE within ±0.50 D
22.5%
Refraction within ±1.00 D
47.5%
Mean postoperative spherical equivalent
-1.74 D
Efficacy index
0.86 score
Safety index
1.32 score
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Visual Outcomes, Footplate Position and Vault Achieved with the Visian Implantable Collamer Lens for Myopic Astigmatism (2021)

3 monthsSTAAR Surgical · EVO Implantable Collamer Lens42 eyes
UDVA 20/20 or better
89%
MRSE within ±0.50 D
74%
Refraction within ±1.00 D
98%
Lost at least 2 lines of CDVA
0% denominator: 42 eyes
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